Rhonda and I go on a Nerd Safari into the jungle of health, nutrition, fitness, performance, and longevity. We visit IGF-1 and whether there’s a tradeoff of having high or low levels. We discuss the PPARs (receptor proteins) and genetic polymorphisms. Does Rhonda think there’s any benefit in a NAD+ booster for health and longevity? Can saunas lower the risk of heart disease, dementia, and all-cause mortality? Rhonda is a wealth of knowledge on so many topics and was the perfect companion to dig into so many fun topics in this episode. She puts a ton of thought into her research and it really shows in this conversation. We discuss: • What Rhonda believes differently today than she did a few years ago [5:40]; • The paradox of GH/IGF-1 in performance and longevity [21:00]; • The role of PPAR in fat metabolism and ketogenic diets [23:00]; • The possible genetic explanations for why some patients don’t respond well to a ketogenic diet [31:00]; • The health benefits of heat and cold exposure [1:12:30]; • NAD+ [1:32:45]; • And more. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram