Episode 459: Why Insulin Matters

In this episode, we shine a spotlight on insulin—an often overlooked but crucial hormone that plays a central role in metabolism and overall health. While blood sugar gets a lot of attention, insulin is the key regulator behind it, influencing energy storage, fat metabolism, and cellular function. We explore how insulin resistance develops, the early signs to watch for, and why it’s so important to address this root issue to prevent chronic disease.

We also discuss how ketogenic and low-carb diets can help regulate insulin levels, improve metabolic flexibility, and support weight management. This episode provides clear, functional insights into insulin’s role and practical strategies for balancing it through nutrition and lifestyle, making it a must-listen for anyone interested in metabolic health and disease prevention.

Also in this episode:

Keto Reset Program - Enrollment opens 8/28! Episode 76 Getting to the root of insulin resistance • What is insulin and why does it matter?

• What is insulin resistance?

• What causes insulin resistance?

• How does it develop on a cellular level?

• What are signs and symptoms of insulin resistance?

• How do we test for insulin resistance?

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• Fasting insulin <8

• C-peptide – Reflects insulin production

• Glucose-insulin index / HOMA-IR – Measures insulin resistance directly (calculated using fasting glucose & fasting insulin)

• Triglyceride:HDL ratio – Optimal <1.5 (higher = higher risk)

• A1c – Goal <5.5% (but early IR won’t always show up here)

• hs-CRP – Inflammation worsens insulin signaling

• Leptin

Keto Checkup Lab • (Fasting Insulin, A1c, Leptin, CMP, DHEA-s)

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• Continuous Glucose Monitor

Nutrisense use code ALIMILLLERD

• Conventional treatment of insulin resistance

Naturally Nourished 323 Ozempic, Wonder Drug or Too Good to be True? Naturally Nourished Episode 359 Oh-No Ozempic Updates, Berberine and Keto •

• Food as medicine for insulin resistance

• Ditch the drivers: eliminate refined carbs, sugar, seed oils, and artificial sweeteners

Top 5 Benefits of Apple Cider Vinegar | Let's make an ACV shooter • Cinnamon, turmeric, fenugreek

• Intermittent fasting

• Movement: Walking after meals

Naturally Nourished Episode 424 How Daily Walking Can Transform your Health •

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• Keto for insulin resistance

A 3-Week Ketogenic Diet Increases Skeletal Muscle Insulin Sensitivity in Individuals With Obesity: A Randomized Controlled Crossover Trial - PubMed Ketogenic Diets for Body Weight Loss: A Comparison with Other Diets Mapping the evolution and impact of ketogenic diet research on diabetes management: a comprehensive bibliometric analysis from 2005 to 2024 •

• Supplements for insulin resistance

Berberine Boost Relax and Regulate EPA DHA Extra Vitamin D Balanced Blend L-Carnitine • ALA

• Chromium & Resveratrol

Multidefense •

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Sponsors for this episode:

This episode is sponsored by our Naturally Nourished Keto Reset Program. Ready to take the guesswork out of keto and finally see real results? Whether you're struggling with weight loss resistance, hormonal imbalances, gut issues, or just want more energy and less bloat—our Keto Reset program is your roadmap. You’ll get a structured, functional medicine approach that goes beyond macros and meal plans. We teach you why your body is stuck and how to heal it from the root—through nutrient-dense food, therapeutic tools, and behavior change strategies that last.

You’ll be supported every step of the way with weekly classes and Q&As, downloads, real food meal plans, and direct access to us This isn’t about restriction or gimmicks. It’s about learning to work with your body, building metabolic flexibility, and unlocking your best health. Doors are open now—so join us, reset your metabolism, and transform your relationship with food, your body, and your health. Grab your spot here.