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Medscape

This podcast delivers Dr. John Mandrola’s summary and perspective on top news of the week that cardiologists can’t miss. This podcast is intended for US health professionals only.

This Week in Cardiology

US doc's pay, the ticagrelor controversy and new RCTs, clopidogrel beats ASA, holding antiplatelets for non-cardiac surgery, and Prof Cleland and ASA dogma are the topics John Mandrola, MD, covers this week.
 
This podcast is intended for healthcare professionals only.
 
To read a partial transcript or to comment, visit:
 
https://www.medscape.com/twic
 
I. US Healthcare
 
Mandrola’s Top 10 Stories in 2024 https://www.medscape.com/viewarticle/mandrolas-top-10-stories-2024-2024a1000mxe?_gl=1*dcvmkh*_gcl_au*MTgzOTY2ODQ0Ni4xNzI5MjU4NjUz
 
 CMS Proposal 
II. Ticagrelor Controversy
 
New Investigation Casts Doubt on Landmark Ticagrelor Trial
 
 https://www.medscape.com/viewarticle/new-investigation-casts-doubt-landmark-ticagrelor-trial-2024a1000n1d
 
 Doshi Review https://www.bmj.com/content/387/bmj.q2550 PLATO https://www.nejm.org/doi/full/10.1056/NEJMoa0904327 ISAR REACT 5 https://www.nejm.org/doi/full/10.1056/NEJMoa1908973 Bates Review https://www.ahajournals.org/doi/epub/10.1161/JAHA.123.031606 Victor Serebuany and Dan Atar Editorial https://doi.org/10.1093/eurheartj/ehp545 
III. New Ticagrelor vs Clopdiogrel trial
 
 Preprint: https://www.medrxiv.org/content/10.1101/2024.11.06.24316875v1.full-text 
IV. Clopidogrel Better Than ASA Even in HBR
 
 Substudy • 
Long-Term Aspirin vs Clopidogrel After Coronary Stenting by Bleeding Risk and Procedural Complexity HOST-EXAM 10.1016/S0140-6736(21)01063-1 • HOST-EXAM-Extended 
https://doi.org/10.1161/CIRCULATIONAHA.122.062770 
V. ASA During Non-Cardiac Surgery
 
 ASSURE DES https://doi.org/10.1016/j.jacc.2024.08.024 
VII. Professor Cleland on ASA for Secondary Prevention
 
 Cleland Editorial https//jamanetwork.com/journals/jamacardiology/article-abstract/2827201 ASA Meta-analysis 10.1016/S0140-6736(09)60503-1 AMIS https://jamanetwork.com/journals/jama/fullarticle/368745 SAPAT 10.1016/0140-6736(92)92619-Q 
You may also like:
 
The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington
 
Questions or feedback, please contact news@medscape.net

Dec 13 2024 This Week in Cardiology

Listener feedback, multiple studies in AF ablation,
 
a DANISH trial substudy of ICDs in NICM, and more data on eye complications of GLP-1 agonists are the topics John Mandrola, MD, covers in this week’s podcast.
 
This podcast is intended for healthcare professionals only.
 
To read a partial transcript or to comment, visit:
 
https://www.medscape.com/twic
 
I. CCTA Feedback
 
 Foy meta-analysis https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2655243 DANCAVAS https://www.nejm.org/doi/full/10.1056/NEJMoa2208681 
II. Listener Feedback on my negative take of the OPTION Trial.
 
 Option trial https://www.nejm.org/doi/pdf/10.1056/NEJMoa2408308 My Preview https://www.medscape.com/viewarticle/mandrola-previews-option-trial-most-worrisome-study-aha-2024-2024a1000kmz 4 Reasons to Question Percutaneous Left Atrial Appendage Closure After AF Ablation • 
https://www.medscape.com/viewarticle/4-reasons-question-percutaneous-left-atrial-appendage-2024a1000l0u 
III. AF Ablation 
 
PVI Add-Ons Provide Better Control of Persistent AF
 
 https://www.medscape.com/viewarticle/pvi-add-ons-provide-better-control-persistent-af-2024a1000lcm
 
 • 
VENUS https://jamanetwork.com/journals/jama/fullarticle/2772281 PROMPT AF https://jamanetwork.com/journals/jama/fullarticle/2826710 STAR AF 2 https://www.nejm.org/doi/full/10.1056/NEJMoa1408288 CRRF-PeAF https://pmc.ncbi.nlm.nih.gov/articles/PMC9241129/ CAVAC trial https://doi.org/10.1161/CIRCEP.124.012917 CRRF-PeAF from multiple centers in Japan (not published) 
IV. DANISH Trial Substudy
 
 Danish Trial Substudy https://www.ahajournals.org/doi/epdf/10.1161/CIRCULATIONAHA.124.071777 Danish Main https://www.nejm.org/doi/full/10.1056/NEJMoa1608029 MADIT-2 EF Substudy https://doi.org/10.1016/S0002-9149(01)01729-5 SCD-HeFT subgroup https://www.nejm.org/doi/full/10.1056/NEJMoa043399 Appraisal of ICD to Prevent SCD https://doi.org/10.1016/j.jacc.2008.05.058 
V. Eye disease and GLP-1 Agonists
 
Jul 26, 2024 This Week in Cardiology Podcast
 
 https://www.medscape.com/viewarticle/1001384
 
 Semaglutide vs No Semagutide and Eye Disease https://link.springer.com/epdf/10.1186/s40942-024-00620-x Semaglutide vs SGLT- Inhibitors and Eye Disease https://www.medrxiv.org/content/10.1101/2024.12.09.24318574v1.full-text 
You may also like:
 
The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington
 
Questions or feedback, please contact news@medscape.net

Dec 20 2024 This Week in Cardiology

PFO closure for recurrent stroke prevention, hormone replacement in women, DAPT, obesity, and fentanyl are discussed in this week's podcast.

Sep 15 Cardiology News

PCSK9 drugs and diabetes, allegations against St Jude Medical, trends in carotid interventions, food as medicine, and death with dignity are discussed by Dr John Mandrola in this week's podcast.

Sep 22 Cardiology News

Oxygen therapy in stroke, physical activity, hospital rankings, MRI labeling of cardiac devices, and PFO closure are discussed in this week's podcast.

Sep 29 Cardiology News

Stopping aspirin, TAVR durability, meditation, triathlon risk, and BP control in low-income patients are discussed by Dr Mandrola in this week's podcast.

Oct 6 Cardiology News

Noninvasive tests for chest pain evaluation, the obesity epidemic, the costs of cardiac device recalls, and DOAC-drug interactions are reviewed in this week's podcast.

Oct 13 Cardiology News

Secondary AF, Heart failure statistics, DOAC bleeding rates, uncontrolled hypertension and stroke risk factors are discussed by John Mandrola in this week's podcast.

Oct 20 Cardiology News

Statins tied to diabetes risk and reduced bacterial infections, a novel use for hs-troponin, mitral-regurgitation management, and His-bundle pacing are reviewed in this week's podcast.

Oct 27 Cardiology News

The ORBITA sham-control PCI study, Watchman, revascularization in cardiogenic shock, Absorb BVS, quality-of-life outcomes after PCI or bypass, and chronic total occlusion PCI are discussed in this week's podcast.

Nov 3 Cardiology News

COVID-19 vaccines and virtual AHA presentations on statins and the nocebo effect, high dose omega-3s, and AF ablation are the topics John Mandrola, MD, discusses on this week’s podcast.

Nov 20, 2020 This Week in Cardiology Podcast

Nov 20, 2020 This Week in Cardiology Podcast

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