Oct 17 2025 This Week in CardiologyAnother knock against the antiplatelet/anticoagulant combo, polypills in HF, the physical exam of the future, and the problem of underpowered trials that even Bayesian analyses cannot rescue are the topics John Mandrola, MD, discusses in this week’s podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I Listener Feedback
Trends Study •
https://www.heartrhythmjournal.com/article/S1547-5271(11)00496-6/fulltext
II Another knock against the Antiplatelet/Anticoagulation combination
“Antiplatelet Plus Oral Anticoagulant Lowers Stroke, Raises Bleeding Risk” https://www.medscape.com/viewarticle/antiplatelet-plus-oral-anticoagulant-lowers-stroke-raises-2025a1000re0
ATIS-NVAF Trial •
https://jamanetwork.com/journals/jamaneurology/fullarticle/2839511 AQUATIC trial •
https://www.nejm.org/doi/abs/10.1056/NEJMoa2507532
III Polypill for HFrEF
A Multilevel Polypill for Patients With HFrEF •
https://www.jacc.org/doi/10.1016/j.jacadv.2025.102195
IV The Physical Exam of the Future
Point-of-Care Ultrasound •
https://doi.org/10.1016/j.jchf.2025.102707
V More on Underpowered Trials – GA vs Moderate Sedation in IV stroke
SEGA Trial •
https://jamanetwork.com/journals/jamaneurology/fullarticle/2839838 Bayesian Analyses of CV Trials •
https://doi.org/10.1016/j.cjca.2021.03.014
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The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington
Questions or feedback, please contact news@medscape.net
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