Eight babies have been born in the UK using genetic material from three people to prevent devastating and often fatal conditions. The method, pioneered by UK scientists, combines the egg and sperm from a mum and dad with a second egg from a donor woman. The technique has been legal in the UK for a decade but this is the first proof it is leading to children born free of incurable mitochondrial disease, which is normally passed from mother to child. Anita Rani is joined by Kat Kitto who has two daughters, one of whom has mitochondrial disease, and Louise Hyslop, consultant embryologist at the Newcastle Fertility Centre, to tell us more.

Hit ITV crime drama Karen Pirie returns to our screens for a second series this weekend, based on the Val McDermid series of novels about a young Scottish detective. Anita is joined in the studio by showrunner, screenwriter and actor Emer Kenny to talk about bringing a new cold case to life for Karen to solve, juggling series two with a newborn, and how she’s managed to combine acting and writing since landing her first big role as Zsa Zsa Carter in EastEnders at the age of 20.

A Government review found that porn involving non-fatal strangulation was "rife" and its prevalence online was contributing to choking, filtering into some people's sex lives - particularly among young people. Last month it was announced that choking will be criminalised in an amendment to the Crime and Policing Bill. To discuss, Anita was joined by Professor Clare McGlynn, Professor of Law at Durham University who contributed to the review, and Dr Jane Meyrick, Associate Professor of Health Psychology at the University of the West of England, who specialises in sexual health and sexual violence.

This week, throughout our series on women and gaming, we’ve heard about the influence that games can have in society. We've spoken to women working in the industry, and found out more about the impact gaming can have on women, but we can’t shy away from the fact that there are still barriers stopping women from accessing games. Anita is joined by to Marie-Claire Isaaman, CEO of Women in Games, Nick Toole, CEO of Ukie, and Stephanie Ijoma, gamer and founder of NNESAGA, to discuss what still needs to change and how the industry can improve.

Presenter: Anita Rani Producer: Corinna Jones