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NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays at 6:30 a.m. ET, with hosts Leila Fadel, Steve Inskeep, Michel Martin and A Martinez. Also available on Saturdays at 9 a.m. ET, with Ayesha Rascoe and Scott Simon. On Sundays, hear a longer exploration behind the headlines with Ayesha Rascoe on "The Sunday Story," available by 8 a.m. ET. Subscribe and listen, then support your local NPR station at donate.npr.org.

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Up First

The CDC quietly rewrites its vaccine guidance online to suggest shots might cause autism, raising new questions about political influence over public health.
President Trump unveils a 28-point Ukraine peace plan that leans on territorial concessions Kyiv has repeatedly rejected. 
And New York City mayor-elect Zohran Mamdani heads to the White House for a meeting with a president who has labeled him a radical threat.

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Jane Greenhalgh, Rebekah Metzler, Megan Pratz, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

Our Executive Producer is Jay Shaylor

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CDC Links Vaccines and Autism, Trump's Ukraine Peace Plan, Mamdani Meets Trump

Former FBI director James Comey’s prosecution hits a major snag after prosecutors admit the grand jury never reviewed his full indictment, raising questions about whether the case can even proceed.
Thousands of already released Epstein documents shed new light on the powerful figures who stayed close to Jeffrey Epstein even after his conviction.
And Nvidia’s staggering earnings and $5 trillion valuation fuel both optimism and warnings about whether the AI boom is entering bubble territory.

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Anna Yukhananov, Megan Pratz, Julia Redpath, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

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Comey Prosecution Troubles, New Findings In Epstein Documents, Nvidia & A.I. Bubble

President Trump defends Saudi Crown Prince Mohammed bin Salman during a White House visit, even as the two leaders unveil sweeping military, nuclear, and investment agreements.

Congress overwhelmingly passes a bill compelling the Justice Department to release its Epstein files, setting up a 30-day countdown that could spark new political fights over redactions.

And a new NPR/PBS News/Marist poll shows Trump at his lowest approval rating of his second term, with voters demanding that he focus on lowering prices as Democrats gain a significant edge heading into 2026.

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Dana Farrington, Kelsey Snell, Megan Pratz, Rebecca Rossman, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

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Trump Defends Saudi Prince, Epstein Bill Passes, Trump Low Approval Rating

The House votes today on whether to force the release of long-awaited Epstein files, a move pushed by a bipartisan coalition despite President Trump’s earlier efforts to stop it. A widening feud between Trump and Marjorie Taylor Greene exposes growing cracks inside the MAGA movement over foreign policy and the “America First” agenda. And President Trump welcomes Saudi Arabia’s crown prince to the White House as both sides seek deeper security and economic ties.

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Kelsey Snell, Megan Pratz, Rebecca Rossman, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

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House Votes On Epstein Files, MAGA Coalition Cracks, Saudi Leader Visits White House

President Trump suddenly reverses course on the Epstein files, urging Republicans to support a House vote on Tuesday that he was previously trying to block. In the Caribbean, a major U.S. military buildup raises new questions about the administration’s strategy toward Venezuela as Trump claims President Maduro “would like to talk.” And in Charlotte, North Carolina, a new Border Patrol operation sparks fear and confusion after immigration enforcement agents fan out across the city with little warning.

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Today’s episode of Up First was edited by Dana Farrington, Tara Neill, Kevin Drew, Mohamad ElBardicy, and Martha Ann Overland.

It was produced by Ziad Buchh, Nia Dumas and Lindsay Totty.

We get engineering support from Damian Herring. And our technical director is Carleigh Strange.

Join us again tomorrow

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Trump's Epstein Reversal, US Military Pressure On Venezuela, Charlotte Border Patrol

President Trump says his Gaza peace plan will end the war between Israel and Hamas and launch a new era of peace in the Middle East. But a month into the ceasefire, progress on implementing the 20-point plan appears to be stalling. Today on The Sunday Story, NPR correspondents Aya Batrawy and Daniel Estrin unpack the ceasefire plan and why it’s not going according to plan. Why is the deal so fragile, and what does this mean for Gaza? And for the first time in over two years of war, NPR goes to the part of Gaza where Israel is fortifying its military occupation.

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What is a ceasefire?

Congress returns to further negotiations on health care subsidies and an earlier-than-expected vote on the Epstein files. President Trump is threatening to sue the BBC over an edit of his speech on January 6, 2021. Russian attacks and a major new corruption probe are the latest developments from Kyiv.

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Congressional To-Do List, Trump V. BBC, Ukraine Update

The White House is calling the recent trove of Epstein documents a "distraction" as both Democratic and Republican lawmakers call for the full release of the Epstein files. In Charlotte, North Carolina, city leaders and residents are scrambling after last-minute notice that Border Patrol agents could arrive within days. And economists warn the government shutdown left lasting scars on the U.S. economy, from lost wages to missing federal data that may never be recovered.

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Dana Farrington, Susanna Capelouto, Rafael Nam, Mohamad ElBardicy and HJ Mai.

It was produced by Ziad Buchh, Nia Dumas and Lindsay Totty

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

Our Executive Producer is Jay Shaylor

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Epstein Files Fallout, Charlotte Immigration Patrols, Economic Impact Of Shutdown

Newly released emails from Jeffrey Epstein’s files include messages linking President Trump to the disgraced financier, as Congress prepares to vote on a bill forcing the release of the full Epstein records. After 43 days, the longest government shutdown in U.S. history ends with a bipartisan deal that leaves Democrats split over what they gained. And with health insurance subsidies still set to expire, millions of Americans could soon face higher premiums unless lawmakers act before year’s end.

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Megan Pratz, Kelsey Snell, Diane Webber, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Lindsay Totty.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

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Epstein Documents Dump, Government Reopens, Affordable Care Act Limbo

House Republicans say they have the votes to end the longest government shutdown in U.S. history, a vote today could send the bill to President Trump’s desk by nightfall. The FAA warns that flight disruptions will continue even after the government reopens, as air traffic controller shortages strain the nation’s aviation system. And the U.S. deploys its largest aircraft carrier to the Caribbean, escalating tensions with Venezuela.

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Today’s episode of Up First was edited by Jason Breslow, Russell Lewis, Andrew Sussman, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Lindsay Totty.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

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House Shutdown Vote, Aviation Challenges, USS Ford Heads to the Caribbean

There are only two days left until Election Day and for both the campaigns of Vice President Kamala Harris and former President Donald Trump swing states are the key to victory. 
In order to help us understand each campaign's strategy, today on the show we feature our colleagues at the NPR Politics Podcast. Host Miles Parks is joined by Domenico Montanaro and Mara Liasson to talk about what each campaign is doing to gain those magical 270 electoral votes needed to win the White House.

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What It Will Take To Get 270

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