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NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays at 6:30 a.m. ET, with hosts Leila Fadel, Steve Inskeep, Michel Martin and A Martinez. Also available on Saturdays at 9 a.m. ET, with Ayesha Rascoe and Scott Simon. On Sundays, hear a longer exploration behind the headlines with Ayesha Rascoe on "The Sunday Story," available by 8 a.m. ET. Subscribe and listen, then support your local NPR station at donate.npr.org.

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Up First

Protesters in Minneapolis return to the streets as federal agents take over the investigation into the killing of a Minnesota woman by an ICE agent, while Portland officials condemn another immigration-related shooting.
A review of immigration related shootings under President Trump shows a rising pattern of violence as federal agents carry out increasingly aggressive and public operations in U.S. cities.
And President Trump signals the U.S. could run Venezuela “much longer” than expected, as oil executives head to the White House to discuss America’s expanded oversight of the country’s future.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Gigi Douban, Rebekah Metzler, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Milton Guevara and Christopher Thomas.

We get engineering support from Zo van Ginhoven. Our technical director is Stacey Abbott.

Our Executive Producer is Jay Shaylor.

(0:00) Introduction
(01:54) Minneapolis Protests
(05:29) Immigration Enforcement Shootings
(09:04) Running Venezuela

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Minneapolis Protests, Immigration Enforcement Shootings, Running Venezuela

Minnesota state law enforcement officials are working with the FBI to investigate the fatal shooting of a Minneapolis woman by an Immigrations and Customs Enforcement officer. 

U.S. forces boarded a tanker carrying sanctioned oil after a two-week chase across the Atlantic, as the Trump administration expands plans to take control of Venezuela’s oil sales indefinitely.

And Health Secretary Robert F. Kennedy Jr.’s new dietary guidelines flip decades of advice, elevating meat and dairy and alarming many public health researchers.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Rebekah Metzler, Kelsey Snell, Kate Bartlett, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from David Greenburg. Our technical director is Stacey Abbott.

And our deputy Executive Producer is Kelley Dickens.

(0:00) Introduction
(01:54) Minnesota ICE Shooting
(05:48) Venezuela Oil Tanker Pursuit
(09:35) RFK Jr's New Dietary Guidelines

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Minnesota ICE Shooting, Venezuela Oil Tanker Pursuit, RFK Jr's New Dietary Guidelines

President Trump talks about next steps for Venezuela, calling for U.S. companies to help rebuild the economy even as much of the existing power structure remains in place.
Facing tough midterm elections in 2026, Trump tells House Republicans he’s struggling to understand voters and leans into culture-war issues rather than cost-of-living concerns.
And European leaders rally around Greenland, pushing back on Trump’s renewed claims that the United States needs the territory for national security.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Rebekah Metzler, Kelsey Snell, Kate Bartlett, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

Our Supervising Producer is Michael Lipkin.

(0:00) Introduction
(01:59) Next Steps In Venezuela
(05:47) GOP 2026 Roadmap
(09:32) Greenland and Europe

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Next Steps In Venezuela, GOP 2026 Roadmap, Greenland and Europe

Ousted Venezuelan president Nicolás Maduro and his wife plead not guilty in New York, after a U.S. military operation brought them out of Venezuela and into a federal courtroom.
Lawmakers are divided after a classified congressional briefing on Venezuela, with Republicans insisting the president acted within the law and Democrats asking what comes next.
And the Centers for Disease Control and Prevention scales back routine childhood vaccine recommendations at President Trump’s direction, some pediatricians warn it could leave more kids vulnerable.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Kelsey Snell, Gigi Douban, Jane Greenhalgh, Mohamad ElBardicy, and HJ Mai.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Stacy Abbott. And our technical director is Neisha Heinis.

Our Supervising Senior Producer is Vince Pearson.

(0:00) Introduction
(1:57) Maduro Pleads Not Guilty
(05:32) Congress on Venezuela
(09:18) Vaccine Schedule Overhaul

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Maduro Pleads Not Guilty, Congress On Venezuela, Vaccine Schedule Overhaul

President Trump says the United States will run Venezuela after U.S. forces seized Nicolás Maduro and his wife in Caracas.
Venezuela’s acting president Delcy Rodriguez shifts from defiance to calls for cooperation as the White House ramps up pressure and threatens further action.
And Nicolás Maduro is set to appear in a New York courtroom, facing drug trafficking, weapons, and narco-terrorism charges that could test the reach of U.S. law overseas.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Andrew Sussman, Tara Neill, Krishnadev Calamur, Mohamad ElBardicy, and HJ Mai.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Neisha Heinis. And our technical director is Carleigh Strange.

(0:00) Introduction
(01:54) U.S. In Venezuela
(05:49) Future Of Venezuela 
(09:46) Maduro In NYC Court

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U.S. In Venezuela, Future Of Venezuela, Maduro In NYC Court

Venezuelan President Nicolas Maduro is in a federal prison in Brooklyn, New York, awaiting trial on charges of narcoterrorism, cocaine-importation conspiracy and weapons charges. The operation to capture Maduro happened in the middle of the night as U.S. troops enjoyed the element of surprise. The U.S. says Maduro is not the legitimate president of Venezuela and accuse him of being the leader of a violent drug cartel.

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Venezuelan President Nicolas Maduro is in New York City, faces narcoterrorism charges

The U.S. bombed the Venezuelan capital Caracas and other areas of the country, and captured Venezuelan President Nicolas Maduro. President Donald Trump said Maduro is being flown to the U.S. and Attorney General Pam Bondi says he will be indicted in the Southern District of New York. The events come after months of escalating U.S. pressure, sending troops and warships to the Carribean.

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The U.S. strikes Venezuela, captures President Maduro

Somali-run day care centers in Minnesota report threats and vandalism after a viral right-wing video accusing them of fraud prompts federal action with nationwide consequences.
The Justice Department misses its deadline to release the Epstein files, fueling confusion and conspiracy theories as heavily redacted and unreliable documents trickle out.
And Switzerland begins days of mourning after a deadly New Year’s Eve fire rips through a crowded nightclub at a ski resort, killing dozens and injuring many more.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Luis Clemens, Dana Farrington, Miguel Macias, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Kaity Kline and Christopher Thomas.

We get engineering support from Stacey Abbott. And our technical director is David Greenburg..

 Our Executive Producer is Jay Shaylor.

(0:00) Introduction
(01:54) Daycare Fraud Claims Fallout
(05:31) Epstein Files Mess 
(09:27) Swiss Nightclub Fire

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Daycare Fraud Claims Fallout, Epstein Files Mess, Swiss Nightclub Fire

Health insurance costs jump for millions after pandemic-era Affordable Care Act subsidies expired overnight. 
The Trump administration freezes child care funding nationwide after targeting Minnesota over unproven fraud claims tied to Somali-run day care centers.
And New York City’s new mayor, Zohran Mamdani, is sworn in at midnight as he prepares to take office.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Carrie Feibel, Cheryl Corley, Andrea De Leon, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

Our deputy Executive Producer is Kelley Dickens.

(0:00) Introduction
(02:33) Health care Subsidies Expire
(05:53) Trump and Minnesota
(10:06) Mamdani Takes Office in NYC

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Healthcare Subsides Expire, Trump and Minnesota, Mamdani Takes Office In NYC

President Trump confirms the first known U.S. strike inside Venezuela, saying it targets drug trafficking as critics warn it risks escalation.
Iranian authorities shut down cities and security forces move in to contain growing protests as anger over inflation and sanctions boils over.

And the flu is spreading fast across the U.S., with a new strain driving cases higher just as vaccination rates slip and hospitals brace for what’s next.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Rebekah Metzler, James Hider, Rebecca Davis, Mohamad ElBardicy, and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

 Our Supervising Producer is Michael Lipkin.

(0:00) Introduction
(03:30) U.S. Strikes Inside Venezuela
(07:25) Iran Protests
(11:22) Flu Cases Surge

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Daycare Fraud Claims Fallout, Epstein Files Mess, Swiss Nightclub Fire

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