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NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays at 6:30 a.m. ET, with hosts Leila Fadel, Steve Inskeep, Michel Martin and A Martinez. Also available on Saturdays at 9 a.m. ET, with Ayesha Rascoe and Scott Simon. On Sundays, hear a longer exploration behind the headlines with Ayesha Rascoe on "The Sunday Story," available by 8 a.m. ET. Subscribe and listen, then support your local NPR station at donate.npr.org.

Support NPR's reporting by subscribing to Up First+ and unlock sponsor-free listening. Learn more at plus.npr.org/upfirst

Up First

Israel struck central Beirut overnight and issued the first ever evacuation order for part of the capital, as Israel vows it will not stop until Hezbollah is defeated and nearly a million people are displaced in Lebanon alone.
The FBI is investigating two separate attacks as acts of terrorism — an armed man drove a car into a Michigan synagogue, and a gunman with a prior ISIS conviction opened fire in a Virginia university classroom, killing one person.
And the Senate passed the largest housing bill in decades with bipartisan support, including a ban on large corporations buying up single-family homes, but it faces an uncertain path with President Trump.

**Correction: In a previous audio version of this episode we mistakenly stated that car that drove into Temple Israel in West Bloomfield, Michigan was packed with explosives.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Hannah Block, Cheryl Corley, Julia Redpath, Kara Platoni, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh and Nia Dumas.

Our director is Christopher Thomas.

We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange

Our Executive Producer is Jay Shaylor.

(0:00) Introduction
(01:54) Israel Bombs Beirut
(05:30) Attacks In Michigan And Virginia
(09:44) Housing Bill

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Israel Bombs Beirut, Attacks In Michigan And Virginia, Housing Bill

Three commercial oil tankers were attacked in the Strait of Hormuz as U.S. and Israeli airstrikes continue on Tehran — Iran may be losing the war in the air, but it is strangling one of the world's most vital waterways and shaking global markets. 
President Trump, who campaigned on bringing gas prices down, is now tapping the strategic petroleum reserve as the war drives prices up.
And the Pentagon has determined the U.S. is responsible for a missile strike on a girls school in Iran that killed at least 165 civilians on day one of the war — NPR has learned the school had been walled off from a nearby military base years before the strike.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Andrew Sussman, Rebekah Metzler, James Hider, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh and Nia Dumas.

Our director is Christopher Thomas.

We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange

Our deputy Executive Producer is Kelley Dickens.

(0:00) Introduction
(01:58) Strait Of Hormuz Crisis
(06:17) Gas Price Politics
(10:25) Iranian School Strike Investigation

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Strait Of Hormuz Crisis, Gas Price Politics, Iranian School Strike Investigation

Defense Secretary Pete Hegseth promised the most intense strikes yet on Iran as residential buildings in Tehran come under fire and Iranian forces target naval ships in the Gulf. 
A new NPR/PBS News/Marist poll finds a majority of Americans oppose the war and President Trump's approval rating on the economy has hit a record low, raising questions about what the conflict means heading into the midterm elections. 
And in Georgia, the special election to replace Marjorie Taylor Greene is heading to a runoff, with Trump's endorsed candidate falling short of an outright win as a Democrat closes in.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Hannah Block, Dana Farrington, Megan Pratz, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh and Nia Dumas.

Our director is Christopher Thomas.

We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange

Our Supervising Producer is Michael Lipkin.

(0:00) Introduction
(01:57) Intense Strikes On Iran
(06:08) Trump Approval Poll
(10:05) Georgia Special Election Runoff

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Intense Strikes On Iran, Trump Approval Poll, Georgia Special Election Runoff

President Trump declared victory in Iran at his first press conference since the war began, but said the U.S. could still go further and compared the endgame to Venezuela, walking back earlier calls for unconditional surrender. 
The war is widening as Israel keeps striking Tehran and Beirut, Iran continues to hit back in the Gulf, and Lebanon's president publicly accuses Hezbollah of betraying the country while signaling he's ready for direct talks with Israel. 
And in New York City, two Pennsylvania teenagers are charged with terrorism after throwing explosive devices at an anti-Muslim protest, with investigators saying they were inspired by ISIS.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Rebekah Metzler, Hannah Block, Alfredo Carbajal, Mohamad ElBardicy and Alice Woelfle.
It was produced by Ziad Buchh and Nia Dumas.
Our director is Christopher Thomas.
We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange
Our Supervising Senior Producer is Vince Pearson.

(0:00) Introduction
(01:58) Trump Declares Early Victory
(06:15) Lebanon Asks Israel To Talk
(10:14) New York Protest Attack

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Trump Declares Early Victory, Lebanon Asks Israel To Talk, New York Protest Attack

Israel struck Tehran's oil facilities as Iran named a new supreme leader, the hardline son of the Ayatollah Israel killed on day one, and a senior Israeli military official tells NPR the war needs three more weeks.
President Trump reversed course on Kurdish fighters entering Iran, and Iraq's Kurdish deputy prime minister tells NPR in his first interview with western media since the war began that the Kurds will not be part of the fight and are not guns for hire.
And the war is strangling the Strait of Hormuz, where hundreds of tankers and container ships are now stranded, raising fears of a global energy crisis.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Hannah Block, Tina Kraja, James Hider, Mohamad ElBardicy and HJ Mai.
It was produced by Ziad Buchh and Ben Abrams.
Our director is Christopher Thomas.
We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange.

(0:00) Introduction
(01:55) Iran War Escalates
(5:17) Kurds Stay Out
(10:52) Global Shipping Crisis

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Iran War Escalates, Kurds Stay Out, Global Shipping Crisis

For years, India was thought of as the Wild West of the fertility industry. But in 2021, a new law in India made it illegal for women to sell their eggs or serve as paid surrogates. That law clashed with a growing demand for human eggs within the country. The result: a thriving black market for human eggs.

Today, some of the most marginalized Indian women and girls are supplying reproductive material, often with little compensation and at great personal risk. This week on The Sunday Story, NPR correspondent Diaa Hadid and co-reporter Shweta Desai investigate the supply chain of human eggs in India, from fertility clinics catering to the wealthy to the slums of Mumbai and Chennai. And we meet women who have given up some of the most intimate parts of themselves—to survive.

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The Human Egg Sellers

More countries in the Middle East reported incoming fire from Iran over the week. Oil prices spike as shippers avoid the Strait of Hormuz. President Trump is attending a summit for Latin American leaders.

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Iran One Week On, Oil Prices Spike, Latin America Meeting

President Trump fired Homeland Security Secretary Kristi Noem and named Senator Markwayne Mullin as his pick to take over, in the first cabinet shakeup of his second term.
The U.S.-Israeli war with Iran is widening again, with Israel striking Beirut’s southern suburbs as Lebanon says tens of thousands have been displaced.
And two months after U.S. forces seized Venezuela’s president, Washington and Caracas are suddenly cutting deals on oil and critical minerals and moving to restore diplomatic relations.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Anna Yukhananov, Hannah Bloch, Tara Neill, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh and Nia Dumas.

Our director is Christopher Thomas.

We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange.

Our Executive Producer is Jay Shaylor.

(0:00) Introduction
(01:53) Trump Fires Kristi Noem
(05:50) Middle East War Latest
(09:44) Venezuela-US Diplomacy

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Trump Fires Kristi Noem, Middle East War Latest, Venezuela-US Diplomacy

Iranians are fleeing as Israel and the U.S. keep striking Iran, the fighting continues in Lebanon, and the war’s spillover is rattling Gulf countries.
President Trump is offering shifting explanations for why the U.S. struck Iran, as the White House tries to line up its message and Americans remain wary about what the war is meant to achieve.
And China says it will send a special envoy to the Middle East as Beijing’s annual “Two Sessions” get underway, with leaders warning the world is getting more volatile even as growth slows at home.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Hannah Bloch, Miguel Macias, James Hider, Tina Kraja, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh and Ben Abrams.

Our director is Christopher Thomas.

We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange.

And our Deputy Executive Producer is Kelley Dickens.

(0:00) Introduction
(02:10) Iran War Expanding
(06:13) Khamenei Successor
(09:49) China Mediates Middle East War

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Iran War Expanding, Khamenei Successor, China Mediates Middle East War

The Middle East war is in its fifth day as the U.S. and Israel keep striking targets across Iran and Lebanon, Iran retaliates into the Gulf, and funeral preparations begin for Supreme Leader Ali Khamenei.
President Trump is offering shifting explanations for why the U.S. struck Iran, as the White House tries to unify its message and Americans remain wary about what the war is meant to achieve.
And the first midterm primary results are in, with Democrats in Texas choosing James Talarico and early races in North Carolina and Arkansas offering a first read on where both parties are headed.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Hannah Bloch, Rebekah Metzler, Dana Farrington, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh, Ana Perez and Nia Dumas

Our director is Christopher Thomas.

We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange.

Our Supervising Producer is Michael Lipkin.

(0:00) Introduction
(01:55) Middle East War Intensifies
(05:58) Trump's Rational For War
(09:36) First Midterm Primaries

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Middle East War Intensifies, Trump's Rational For War, First Midterm Primaries

Research shows that psychedelics can help with a range of mental health conditions, like PTSD and depression. So why can't you get them from your doctor? Today on The Sunday Story, we take a trip through some of the latest science behind psychedelic therapy, and efforts to bring these mind‑altering drugs into the mainstream. Plus, what's ketamine got to do with it?

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Can Psychedelic Therapy Go Mainstream?

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