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Dr. Mark Hyman

Welcome to The Dr. Hyman Show, the groundbreaking podcast redefining health in America and empowering you to take ownership of your health. Hosted by Dr. Mark Hyman—this show tackles the most pressing issues of our time: chronic disease, mental health, food policy and controversy, prevention and recovery, and longevity. In an era where our food system fuels disease and outdated healthcare models fail to address root causes, Dr. Hyman delivers evidence-based insights and expert interviews to help you become the CEO of your own health—something your doctor isn’t doing.
The Dr. Hyman Show goes beyond the headlines to reimagine a food and healthcare system that protects health, unburdens our economy from the weight of chronic disease, supports the environment, and secures a vibrant future for all Americans. Whether you’re looking for cutting-edge protocols to transform your health, strategies to combat the chronic disease epidemic, or deep conversations about how wellness intersects with food, politics, and the environment, this podcast is your trusted guide. Rethink disease, claim your health, and join the movement for a healthier nation—tune into The Dr. Hyman Show today!

The Doctor's Farmacy with Mark Hyman, M.D.

With so much conflicting health advice online, it’s no wonder people feel overwhelmed by food choices. Is saturated fat really the enemy? Are seed oils as harmful as some headlines claim? And how do we know what’s actually true? 

In this episode of The Dr. Hyman Show, I sit down with nutrition researcher and author Simon Hill to make sense of the latest science and help you cut through the confusion.

You can watch our full conversation on YouTube or listen wherever you get your podcasts.

We discuss:

• The real story behind seed oils, saturated fat, and inflammation—and what to do about it

• What your lab work can tell you about your unique nutrition needs

• How to spot nutrition misinformation and think critically about food trends

• Why cutting back on ultra-processed foods may be more important than obsessing over any single nutrient

In a world full of nutrition noise, this episode helps you tune into what really matters—science, and your own body.

View Show Notes From This Episode

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This episode is brought to you by Fatty15, Paleovalley, Function Health, AirDoctor, Timeline and Pique.

Head to fatty15.com/hyman and use code HYMAN for 15% off your 90-day subscription Starter Kit.

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Join today at FunctionHealth.com/Mark and use code HYMAN100 to get $100 toward your membership.
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The Truth About Seed Oils, Protein & What’s Actually Making Us Sick | Simon Hill

Medicine stands at the threshold of a new era, where artificial intelligence and systems biology are working hand in hand to make care more personal, predictive, and precise than ever before. 

AI is already improving diagnostic accuracy, automating administrative tasks, and uncovering patterns in data—like retinal scans or genomics—that humans often miss. 

Rather than replacing doctors, AI enhances their ability to deliver more informed, precise, and efficient care. At the same time, individuals are gaining tools—from at-home diagnostics to wearable biosensors—that empower them to track and optimize their own health. 

This shift marks a move from reactive, disease-centered care to a proactive, data-driven model of scientific wellness.

In this episode, I talk with Dr. Eric Topol, Dr. Nathan Price, Dr. Leroy Hood, Dr. Vijay Pande, and Daisy Wolf about how artificial intelligence, personalized data, and wearable technology are converging to radically transform medicine.

Dr. Eric Topol is Executive Vice President of Scripps Research and founder/director of its Translational Institute, recognized as one of the top 10 most cited researchers in medicine with over 1,300 publications. A cardiologist and author of several bestselling books on the future of medicine, he leads major NIH grants in precision medicine and shares cutting-edge biomedical insights through his Ground Truths newsletter and podcast.

Dr. Nathan Price is Chief Scientific Officer at Thorne HealthTech, author of The Age of Scientific Wellness, and a National Academy of Medicine Emerging Leader. He also serves on the Board on Life Sciences for the National Academies and is Affiliate Faculty in Bioengineering and Computer Science at the University of Washington.

Dr. Leroy Hood is CEO and founder of Phenome Health, leading the Human Phenome Initiative to sequence and track the health of one million people over 10 years. A pioneer in systems biology and co-founder of 17 biotech companies, he is a recipient of the Lasker Prize, Kyoto Prize, and National Medal of Science.

Dr. Vijay Pande is a General Partner at Andreessen Horowitz and founder of a16z Bio + Health, managing over $3 billion in life sciences and healthcare investments at the intersection of biology and AI. An Adjunct Professor at Stanford, he is known for his work in computational science, earning honors like the DeLano Prize and a Guinness World Record for Folding@Home.

Daisy Wolf is an investing partner at Andreessen Horowitz, specializing in healthcare AI, consumer health, and healthcare-fintech innovation. She previously worked at Meta and in various startups, holds a JD from Yale Law, an MBA from Stanford, and a BA from Yale, and is based in New York City.

This episode is brought to you by BIOptimizers.

Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Full-length episodes can be found here:

Can AI Fix Our Health and Our Healthcare System?

The Next Revolution In Medicine: Scientific Wellness, AI And Disease Reversal

The Future of Healthcare: The Role of AI and Technology

Inside the New Era of Precision Medicine: Where AI and Human Insight Unite

This special bonus episode features Dr. Todd LePine from the UltraWellness Center, diving into how functional medicine can help reverse fatty liver disease—an often-overlooked condition that’s quietly affecting millions. While conventional care may miss early warning signs or focus solely on medication, Dr. LePine and I take a deeper look at the root causes.

We also walk through a real patient case that shows how liver fat can be reduced and overall health restored through personalized nutrition and lifestyle changes. If you or someone you know has ever been told their liver enzymes are “a little high,” this is a conversation you won’t want to miss.

You’ll learn:

• Why you could have fatty liver disease—even if you're not overweight or drinking

• What elevated liver enzymes really mean for your long-term health

• How to protect your liver by cutting out hidden sources of sugar and toxins

• Which foods and supplements support detox, reduce inflammation, and repair damage

• What a real-life recovery looks like and how functional medicine makes it possible

This is part of a limited bonus series spotlighting the work of the UltraWellness Center team, with new episodes dropping monthly on select Fridays. To learn more about the UltraWellness Center or inquire about becoming a patient, visit: https://ultrawellnesscenter.com

Bonus Episode: Reversing Fatty Liver at the UltraWellness Center

Our healthcare system is broken—and it’s not by accident. On this episode of The Dr. Hyman Show, I’m joined by Brigham Buhler, a former pharmaceutical rep turned healthcare entrepreneur, to explore how misaligned incentives across pharma, insurance, and government are undermining patient care. 

This conversation is about more than just exposing the problem. It’s about empowering individuals. Watch our full discussion on my YouTube channel here - https://youtu.be/062lululORA

We discuss:

• How hidden financial incentives could be affecting the care you receive

• Why even well-meaning doctors may be limited in helping you heal—and what you can do about it

• What to watch out for when navigating insurance, prescriptions, and denied claims

• How you can prioritize prevention, even when it’s not supported

Navigating the healthcare system can be overwhelming, but your next step doesn’t have to be. With the right insight, you can take back control and advocate for the care you deserve.

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

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Sign Up for Dr. Hyman’s Weekly Longevity Journal

https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Join the 10-Day Detox to Reset Your Health

https://drhyman.com/pages/10-day-detox

Join the Hyman Hive for Expert Support and Real Results

https://drhyman.com/pages/hyman-hive

This episode is brought to you by Seed, BON CHARGE, Paleovalley, PerfectAmino and Big Bold Health.

Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Head to boncharge.com and use code DRMARK for 15% off your order.

Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase.

Go to bodyhealth.com and use code HYMAN20 for 20% off your first order.

Get 30% off HTB Immune Energy Chews at bigboldhealth.com and use code DRMARK30.

Pharma Whistleblower Reveals Who Really Runs American Healthcare w/ Brigham Buhler

Social media platforms are designed to hijack our brain’s reward system, keeping us hooked through endless dopamine hits. This constant stimulation fragments our attention, reshapes our behavior, and can lead to burnout, anxiety, and even addiction—especially in developing brains. The more we scroll, the more we crave quick hits of novelty, making it harder to tolerate boredom or engage in deeper, more meaningful tasks. And while adults may struggle, kids are even more vulnerable, facing emotional dysregulation and long-term brain changes. The good news? Awareness is the first step toward reclaiming agency and creating healthier boundaries in a world built for distraction.

Jonathan Haidt is a social psychologist, bestselling author, and professor at NYU’s Stern School of Business. His research focuses on the moral foundations of culture and politics, exploring why good people are divided by religion, ideology, and values. He is the author of The Happiness Hypothesis, The Righteous Mind, and The Coddling of the American Mind (co-authored with Greg Lukianoff), and has given four widely viewed TED talks. Haidt is also a co-founder of Heterodox Academy, the Constructive Dialogue Institute, and Ethical Systems—organizations that promote viewpoint diversity, constructive disagreement, and ethical leadership. Since 2018, he has turned his attention to the mental health crisis among teens and the role of social media in political polarization. His latest book, The Anxious Generation: How the Great Rewiring of Childhood is Causing an Epidemic of Mental Illness, was published in 2024. In 2019, he was inducted into the American Academy of Arts and Sciences.

Cal Newport is an associate professor of computer science at Georgetown University. In addition to researching cutting-edge technology, he also writes about the impact of these innovations on our culture. Newport is the author of six books, including Slow Productivity, Digital Minimalism, and Deep Work. His work has been featured in many publications, including the New York Times, the Wall Street Journal, and the Economist, and he has been writing essays for his personal website (CalNewport.com) for over a decade. He has never had a social media account.

Tobias Rose-Stockwell is a writer, designer, and media researcher whose work has been featured in major outlets such as The Atlantic, WIRED, NPR, the BBC, CNN, and many others. His research has been cited in the adoption of key interventions to reduce toxicity and polarization within leading tech platforms. He previously led humanitarian projects in Southeast Asia focused on civil war reconstruction efforts, work for which he was honored with an award from the 14th Dalai Lama. He lives in New York with his cat Waffles.

This episode is brought to you by BIOptimizers.

Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Full-length episodes can be found here:

How to Protect Your Child’s Mental Health from the Dangers of Social Media

How Social Media May Be Ruining Your Life

How Social Media And AI Impacts Our Mental Health: Reclaiming Our Minds And Hearts And Healing A Divided World

Scrolling Ourselves Sick: The Hidden Cost of Constant Connection

On this episode of The Dr. Hyman Show, we’re exploring the emerging science of metabolic psychiatry. My guest, Dr. Iain Campbell, is a researcher at the University of Edinburgh and someone who has lived with bipolar disorder himself. He brings a rare dual perspective as both a scientist and a patient to this critical conversation. 

Together, we discuss what’s really driving psychiatric conditions like bipolar disorder and why a systems-based approach may hold the key to meaningful recovery. 

Catch our full conversation on YouTube here - https://youtu.be/YCcZb2H2Ceg

We unpack:
• What it means when mental health symptoms start in the body—not just the brain

• How to tell if metabolism, sleep, or inflammation are driving your mood swings

• Why seasonal changes impact energy and mood, and how you can stay steady year-round

• When keto might help where meds haven’t, and what to know before trying it

• How to catch metabolic red flags before they affect your mental health

When we shift how we see mental health, real healing becomes possible. There are answers, and this episode can help you find them.

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Sign Up for Dr. Hyman’s Weekly Longevity Journal

https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Join the 10-Day Detox to Reset Your Health

https://drhyman.com/pages/10-day-detox

Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive

This episode is brought to you by Sunlighten, Paleovalley, AirDoctor and LMNT.
Visit sunlighten.com and save up to $1400 on your purchase with code HYMAN.

Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase.

Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman.

Get a free LMNT Sample Pack with any order—just head to drinklmnt.com/hyman.

Is Bipolar Disorder Really a Diet Problem w/ Dr. Iain Campbell

ADHD and other brain-based conditions such as depression, autism, and even schizophrenia are increasingly understood as inflammatory disorders of the brain—deeply rooted in the complex interplay between genetics, environment, and lifestyle. Many individuals go undiagnosed for years, internalizing harmful labels like “lazy” or “difficult,” until the weight of unaddressed symptoms finally becomes too much. But there is hope: Functional Medicine offers a radically different approach by uncovering and addressing root causes such as nutritional deficiencies, gut microbiome imbalances, food sensitivities, toxin exposures, and lifestyle factors. Stories of transformation emerge when these root drivers are corrected—children once labeled disruptive begin to thrive, adults regain focus and emotional balance, and families find relief. This emerging paradigm offers not just symptom management but the possibility of genuine healing through personalized, whole-body care.

In this episode, I discuss, along with Dr. George Papanicolaou and Dr. Jaquel Patterson, how ADHD and other mental health challenges are often rooted in inflammation and imbalances in the body—and how addressing diet, lifestyle, and root causes can lead to real healing.

Dr. Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is Board Certified in Family Medicine from Abington Memorial Hospital. Over time as the healthcare system made it harder for patients to receive personal care, Dr. Papanicolaou decided a change was needed. He began training in Functional Medicine through the Institute of Functional Medicine. In 2015, he established Cornerstone Personal Health—a practice dedicated entirely to Functional Medicine. In August 2017, I invited Dr. Papanicolaou to join The UltraWellness Center and we’ve been successfully helping people together ever since.

Dr. Jaquel Patterson is a nationally recognized naturopathic physician, success coach, three-time Amazon bestselling author, and Forbes contributor. She owns a successful medical practice, Fairfield Family Health in Connecticut, and brings over 16 years of clinical experience, specializing in Lyme disease, autoimmune conditions, integrative psychiatry, and environmental medicine. A sought-after speaker, Dr. Patterson has been featured in USA Today, New York Magazine, and Forbes, and on CBS, Fox, NBC, and ABC. She’s the past president of the American Association of Naturopathic Physicians and currently serves on the board of the American Academy of Environmental Medicine. Certified by the Institute for Functional Medicine (IFM), she’s also completed a fellowship in functional medicine with a focus on psychiatry and ADD/ADHD. In addition to her naturopathic medical degree, Dr. Patterson holds an MBA in Healthcare Management from Quinnipiac University and an undergraduate degree from Cornell University.

This episode is brought to you by BIOptimizers.

Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Full-length episodes can be found here:Why ADHD Is Not A Psychiatric Disorder Or Brain Disease

What’s Fueling Our Mental Health Crisis and How Can We Fix it?

7 Strategies To Address ADHD

Rethinking ADHD: Root Causes, Real Healing, and the Power of Functional Medicine

On this episode of The Doctor Hyman Show, I sit down with Dr. Eric Topol—renowned cardiologist, geneticist, and founder of the Scripps Research Translational Institute—to talk about the future of disease prevention. From AI diagnostics to genetic risk scoring, we explore the tools that could help stop Alzheimer’s and other chronic diseases before they start.

This is one of the most hopeful conversations I’ve had about what’s ahead. Watch it on YouTube here.

We discuss:

• How new diagnostics and AI tools could help detect Alzheimer’s early

• The key lab tests and biomarkers to know—and how to talk to your doctor about them

• Why tracking your health data over time matters more than you think

• What you can do to strengthen your immune system and lower disease risk

We have more power than ever to take control of our health. This episode shows you where to start.

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Sign Up for Dr. Hyman’s Weekly Longevity Journal

https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Join the 10-Day Detox to Reset Your Health

https://drhyman.com/pages/10-day-detox

Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive

This episode is brought to you by Seed, Pique, fatty15 and AirDoctor.
Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Receive 20% off FOR LIFE + a free Starter Kit with a rechargeable frother and glass beaker at Piquelife com/Hyman.

Head to fatty15.com/hyman and use code HYMAN for 15% off your 90-day subscription Starter Kit.Get cleaner air. 

Right now, you can get up to $300 off at airdoctorpro.com/drhyman.

How to Catch Alzheimer’s Before It Starts, with Dr. Eric Topol

Longevity isn’t just about adding years to life—it’s about adding life to those years. At the heart of lasting vitality are the often-overlooked essentials: deep social connection, a clear sense of purpose, and a mindset filled with optimism. These emotional and relational foundations are just as critical as what’s happening inside the body. Thanks to emerging diagnostics and the growing field of functional and longevity medicine, we now have the ability to detect subtle shifts in biology—long before symptoms arise—giving us the chance to course-correct with personalized strategies. By combining cutting-edge science with time-tested lifestyle practices like nourishing food, regular movement, restful sleep, and meaningful relationships, we can not only slow the aging process but begin to reverse it—unlocking a future where growing older means growing stronger, wiser, and more vibrant.

In this episode, I explore, along with Peter Diamandis and Dr. Jeffrey Bland the keys to living a longer, healthier life by combining cutting-edge longevity science with the power of mindset, purpose, and meaningful connection. 

Peter Diamandis is the founder and executive chairman of the XPRIZE Foundation, which leads the world in designing and operating large-scale incentive competitions. He was recently named by Fortune as one of the “World’s 50 Greatest Leaders.” He is also the executive founder of Singularity University, a graduate-level Silicon Valley institution that counsels the world's leaders on exponentially growing technologies.

Dr. Jeff Bland is the founder of Big Bold Health, a company on a mission to transform the way people think about one of nature’s greatest innovations—the immune system. Through Big Bold Health, Dr. Bland is advocating for the power of Immuno-Rejuvenation to enhance immunity at a global level, often through the rediscovery of ancient food crops and superfoods. To get there, he is building a network of small farms and suppliers throughout the US that take a clear stance on regenerative agriculture, environmental stewardship, and planetary health. Dr. Bland’s career in health spans more than 40 years. A nutritional biochemist by training, he began in academia as a university professor. He then spent three decades in the natural products industry, working alongside other pioneers. A lifelong educator, Dr. Bland has traveled the world many times over in his role as the “father of functional medicine.” In 1991, he and his wife, Susan, founded The Institute for Functional Medicine. In 2012, he founded another educational nonprofit called the Personalized Lifestyle Medicine Institute. Dr. Bland is the author of The Disease Delusion: Conquering the Causes of Chronic Illness for a Healthier, Longer, and Happier Life, as well as countless additional books and research papers.

This episode is brought to you by BIOptimizers.

Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Full-length episodes can be found here:

The Emerging Science Of LongevityThe Surprising Key To LongevityThe Science Of Eating For Longevity

The Longevity Code: How Purpose, Connection, and Science Are Rewriting Aging Episode Description:

What if the key to healing depression isn’t another pill but a profound shift in consciousness? 

On this episode of The Dr. Hyman Show, I talk with Dr. Robin Carhart-Harris, one of the world’s leading psychedelic researchers, about how these compounds unlock plasticity in the brain and offer new hope for people with treatment-resistant mental health challenges.

From trauma recovery to the entropic brain principle, this is a conversation that challenges everything we think we know about the mind. You can watch the full episode on YouTube - https://youtu.be/P0EDsfPwbUQ

In this episode, you’ll learn:

• What happens in the brain during a psychedelic experience and why it matters
• How the right set, setting, and support can shape the outcome of your healing journey
• Why some people improve after one session, while others need a longer path
• The risks of self-medicating and how to explore psychedelics safely
• How emerging tools, including AI, could help personalize treatment and improve recovery

If you’re curious about the healing potential of psychedelics, this is an honest, research-backed conversation worth tuning into.

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Sign Up for Dr. Hyman’s Weekly Longevity Journal

https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Join the 10-Day Detox to Reset Your Health

https://drhyman.com/pages/10-day-detoxJoin the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive

This episode is brought to you by BON CHARGE, PerfectAmino, Timeline and Big Bold Health.

Head to boncharge.com and use code DRMARK for 15% off your order.

Go to bodyhealth.com and use code HYMAN20 for 20% off your first order.

Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today.

Get 30% off HTB Immune Energy Chews at bigboldhealth.com and use code DRMARK30.

How to Catch Alzheimer’s Before It Starts, with Dr. Eric Topol

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