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Sean Carroll | Wondery


Ever wanted to know how music affects your brain, what quantum mechanics really is, or how black holes work? Do you wonder why you get emotional each time you see a certain movie, or how on earth video games are designed? Then you’ve come to the right place. Each week, Sean Carroll will host conversations with some of the most interesting thinkers in the world. From neuroscientists and engineers to authors and television producers, Sean and his guests talk about the biggest ideas in science, philosophy, culture and much more.


Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

The world is becoming pixelated. As computers and other digital devices become ubiquitous, human knowledge and communication and information is gradually being converted into, and manipulated as, strings of bits. What does that really mean, and what are the ramifications going forward? Alvy Ray Smith is a computer scientist, co-founder of Pixar, and author of A Biography of the Pixel. We go through the journey of how he helped make computer animation a reality, and the implications of what he calls the "Great Digital Convergence."

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/08/18/325-alvy-ray-smith-on-pixar-pixels-and-the-great-digital-convergence/

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Alvy Ray Smith received a Ph.D. in computer science from Stanford University. He has been a professor of electrical engineering and computer science at New York University, a member of the Computer Graphics Lab at the NY Institute of Technology, director of computer graphics at Lucasfilm, and cofounder of Pixar and Altamira. He is a member of the National Academy of Engineering and a Fellow of the America Association for the Advancement of Science as well as the American Society of Genealogists. He is the winner of two technical Academy Awards.

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325 | Alvy Ray Smith on Pixar, Pixels, and the Great Digital Convergence

It is not manifestly obvious that universities should be where most scholarly research is performed. One could imagine systems that separated out the tasks of "teaching students" and "generating new knowledge." But it turns out that combining them yields spectacular synergies, both from letting students experience cutting-edge research and from keeping researchers inspired by interacting with bright young minds. Today we talk to Elizabeth Mynatt, Dean of Computer Sciences at Northeastern, both about her own research in "human-centered computing," and about the bigger-picture issues of why basic research is important, and why universities are such good places to do it.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/08/11/324-elizabeth-mynatt-on-universities-and-the-importance-of-basic-research/

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Elizabeth Mynatt received a Ph.D. in computer science from the Georgia Institute of Technology. She is currently Dean of the Khoury College of Computer Sciences at Northeastern University. She is a senior investigator with Emory’s Cognitive Empowerment Program and co-PI for the NSF AI-CARING Institute. She is a fellow of the Association for Computing Machinery and the American Association for the Advancement of Science, and a member of the American Academy of Arts and Sciences. She was lead author on the National Academies report, "Information Technology Innovation: Resurgence, Confluence, and Continuing Impact."

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324 | Elizabeth Mynatt on Universities and the Importance of Basic Research

Welcome to the August 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!

Blog post with questions and transcript: https://www.preposterousuniverse.com/podcast/2025/08/04/ama-august-2025/

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AMA | August 2025

The search for a foundational theory of quantum mechanics that all physicists can agree on remains active. Over the last century a number of contenders have emerged, including Many-Worlds, pilot-wave theories, and others, but all of them have aspects that many people object to. Jacob Barandes has taken up the challenge, proposing a new formulation of quantum theory in which there is no wave function, only real degrees of freedom with fundamentally stochastic dynamics. We talk about this new theory and the challenges facing it.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/07/28/323-jacob-barandes-on-indivisible-stochastic-quantum-mechanics/

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Jacob Barandes received his Ph.D. in physics from Harvard University. He is currently Senior Preceptor in Physics and Associated Faculty in Philosophy at Harvard. He teaches both physics and philosophy courses at Harvard, where he has been the recipient of several teaching awards.

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323 | Jacob Barandes on Indivisible Stochastic Quantum Mechanics

When we think of the capacities that distinguish humans from other species, we generally turn to intelligence and its byproducts, including our technological prowess. But our intelligence is highly connected to our ability to use language, which is in turn closely related to our capacities as social creatures. Philosopher Philip Pettit would encourage us to think of those social capacities, as enabled by language, as the primary locus of what makes humans different, as discussed in his new book When Minds Converse: A Social Genealogy of the Human Soul. And that linguistic aptitude helps us understand the nature of agency, responsibility, and freedom.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/07/21/322-philip-pettit-on-language-agency-politics-and-freedom/

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Philip Pettit received his Ph.D. in philosophy from University College Belfast. He is currently Laurance S. Rockefeller University Professor of Human Values at Princeton University and Distinguished University Professor of Philosophy at Australian National University. He is a Fellow of the Academy of Social Sciences in Australia, the Australian Academy of the Humanities, the American Academy of Arts and Sciences, and the Guggenheim Foundation, among other honors.

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322 | Philip Pettit on Language, Agency, Politics, and Freedom

Quantum field theory is the basis for our most successful theories of fundamental physics. And yet, there are things we don't understand about it. Some of these puzzles are relatively well-known, while others are less celebrated. David Tong joins us to talk about some of the more interesting and perplexing aspects of quantum field theory. He also discusses his new project to write a series of textbooks covering (all?) important topics in theoretical physics. To date, these include Classical Mechanics, Quantum Mechanics, Fluid Mechanics, and Electromagnetism.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/07/14/321-david-tong-on-open-questions-in-quantum-field-theory/

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David Tong received his Ph.D. in theoretical physics from Swansea University. He is currently a professor of Theoretical Physics in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge. He is a winner of the Adams Prize and a Simons Investigator. In addition to his books, he has written many freely-available sets of lecture notes on topics in physics.

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321 | David Tong on Open Questions in Quantum Field Theory

Welcome to the July 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!

Blog post with questions and transcript: https://www.preposterousuniverse.com/podcast/2025/07/07/ama-july-2025/

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

AMA | July 2025

Our universe started out looking very simple: hot, dense, smooth, rapidly expanding. According to our best current model, it will end up looking simple once again: cold, dark, empty. It's in between -- now, roughly speaking -- that things look complex. I have been working to understand the stages by which complexity comes into existence, thrives, and eventually disappears. Without going into technical details, in this solo episode I give an overview of the general picture and the clues we are looking at to better understand the process of complexogenesis.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/06/30/320-solo-complexity-and-the-universe/

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The Santa Fe Institute has recently published a four-volume set of classic papers on complexity. David Krakauer provided a comprehensive introduction that has been published as a standalone book.

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320 | Solo: Complexity and the Universe

It is common to refer to philosophy as "a series of footnotes to Plato." But in the original quote, Alfred North Whitehead was more careful: he limited his characterization to "the European philosophical tradition." There are other traditions, both ancient and ongoing: Chinese philosophy, Indian philosophy, Africana philosophy, and various indigenous philosophies. For the most part, these do not get nearly as much attention in European and American schools as the European tradition does. Bryan Van Norden argues for expanding philosophy's geographical scope, to the benefit of philosophy in general.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/06/23/319-bryan-van-norden-on-philosophy-from-the-rest-of-the-world/

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Bryan Van Norden received his Ph.D. in philosophy from Stanford University. He is currently James Monroe Taylor Chair in Philosophy at Vassar College and Chair Professor in the School of Philosophy at Wuhan University. Among his books are Introduction to Classical Chinese Philosophy and Taking Back Philosophy: A Multicultural Manifesto. He is a recipient of Fulbright, National Endowment for the Humanities, and Mellon fellowships.

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319 | Bryan Van Norden on Philosophy From the Rest of the World

Economics is seeing an upsurge in the importance of controlled, reproducible empirical studies. One area where this has had a great impact is on development economics, which studies the economies of low- and middle-income societies. Edward Miguel has been at the forefront of both the revolution in empirical methods, and in applying those techniques to alleviating poverty in sub-Saharan Africa and elsewhere.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/06/16/318-edward-miguel-on-the-developing-practice-of-development-economics/

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Edward Miguel received his Ph.D. in economics from Harvard university. He is currently Distinguished Professor of Economics and Oxfam Professor in Environmental and Resource Economics at the University of California, Berkeley. He is also Faculty co-Director of the Center for Effective Global Action and a Faculty Research Associate of the National Bureau of Economic Research. Among his awards are the Frisch Medal of the Econometric Society, the Kenneth Arrow Prize of the International Health Economics Association, and multiple teaching awards.

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318 | Edward Miguel on the Developing Practice of Development Economics

As a semi-outsider, it’s fun for me to watch as a new era dawns in biology: one that adds ideas from physics, big data, computer science, and information theory to the usual biological toolkit. One of the big areas of study in this burgeoning field is the relationship between the basic bioinformatic building blocks (genes and proteins) to the macroscopic organism that eventually results. That relationship is not a simple one, as we’re discovering. Standard metaphors notwithstanding, an organism is not a machine based on genetic blueprints. I talk with biologist and information scientist Michael Levin about how information and physical constraints come together to make organisms and selves.

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Michael Levin received his Ph.D. in genetics from Harvard University. He is currently Distinguished Professor and Vannevar Bush Chair in the Biology department at Tufts University, and serves as director of the Tufts Center for Regenerative and Developmental Biology. His work on left-right asymmetric body structures is on Nature’s list of 100 Milestones of Developmental Biology of the Century.

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132 | Michael Levin on Growth, Form, Information, and the Self

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