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The Guardian

Twice a week, the Guardian brings you the latest science and environment news

Science Weekly

A trial is under way to find out if a £100 blood test could transform the way that the NHS diagnoses Alzheimer’s disease. Alzheimer’s is the leading cause of dementia and diagnosis is currently costly and time-consuming. To find out how this blood test could benefit patients, Ian Sample talks to Prof Jonathan Schott, who is co-leading the trial. He explains what the test involves and why it could pave the way for exciting new treatments for the devastating disease. Help support our independent journalism at theguardian.com/sciencepod

Is there hope on the horizon for patients with Alzheimer’s?

The murder of political activist Charlie Kirk has prompted fears about rising levels of political violence in the US after a number of high-profile assassinations and attempted assassinations of political figures in recent years. But how connected are these events and do they signal a rise in public support for this kind of violence? To find out Ian Sample speaks to Sean Westwood, an associate professor in political science at Dartmouth College and director of the Polarization Research Lab. He explains how political violence has evolved and why overestimating the support for such acts can be dangerous. Help support our independent journalism at theguardian.com/sciencepod

Is the US on the brink of a new era of political violence?

At a recent ceremony for world leaders in Beijing, a hot mic picked up a surprising exchange between Vladimir Putin and Xi Jinping about the possibility of living to 150. Putin suggested the secret might lie in repeated organ transplants. But is this the new frontier of anti-ageing research or a fringe and unproven theory? To find out, science editor Ian Sample speaks to Russian affairs reporter Pjotr Sauer and to John S Tregoning, professor of vaccine immunology at Imperial College London and author of Live Forever: A Curious Scientist’s Guide to Wellness, Ageing and Death. Help support our independent journalism at theguardian.com/sciencepod

Putin’s quest for longevity

The fertility rate in England and Wales has fallen for the third year in a row – a trend mirrored across the world, with two-thirds of the global population now living in countries with below-replacement-level fertility. In the second episode of a two-part series, Madeleine Finlay speaks to Dean Spears, assistant professor of economics at the University of Texas at Austin, and Dr Jennifer Sciubba, chief executive of the Population Reference Bureau, to ask whether declining birth rates are really something to worry about – and how societies can adapt to a future with fewer children. Watch the new Guardian documentary Between Moon Tides. Help support our independent journalism at theguardian.com/sciencepod

Shrinking states: a positive future with fewer people?

The fertility rate in England and Wales has fallen for the third year in a row. It is a story that is being repeated all over the world, with two thirds of the global population now living in countries with below replacement level fertility. Low fertility rates have become a talking point on the political right, with Elon Musk claiming that population decline is an existential threat to the future of humanity. But for others, the timescales involved are too vast to start worrying about now. So how should we be thinking about population decline? In episode one of a two-part series, Madeleine Finlay speaks to Dean Spears, assistant professor of economics at the University of Texas at Austin, and to Dr Jennifer Sciubba, president and CEO of the Population Reference Bureau, to find out what has happened to global birth rates, and how governments are trying to tackle the fall. Help support our independent journalism at theguardian.com/sciencepod

Shrinking states: are we on a path to depopulation?

Psychologists have traditionally believed we become less curious as we age, but recent research has shown that curiosity actually becomes more targeted and specific in our later years. To find out why this happens, and how maintaining broad curiosity into older age can help keep our brains young, Madeleine Finlay hears from Dr Mary Whatley, an assistant professor of psychology at Western Carolina University, and Dr Matthias Gruber, of Cardiff University’s Brain Imaging Centre. Help support our independent journalism at theguardian.com/sciencepod

Is curiosity the key to ageing well?

It’s been a dramatic week at the US Centres for Disease Control and Prevention (CDC). In the space of seven days, the agency’s head was sacked and replaced by an interim head, four senior staff members resigned, and existing staff took to the streets to express support for their ousted leaders. To understand how everything unfolded and what it could mean for the health of Americans, science editor Ian Sample hears from health reporter Melody Schreiber and former CDC director Mandy Cohen. Help support our independent journalism at theguardian.com/sciencepod

RFK Jr and the chaos at the CDC

There are increasing reports of people experiencing delusions after intensive use of AI chatbots. The phenomenon, dubbed ‘AI psychosis’, has raised concerns that features built into large language models may contribute to some users losing touch with reality. Madeleine Finlay speaks to Dr Hamilton Morrin, a psychiatrist and researcher at King’s College London, about his recent preprint exploring who is at risk and how models could be made safer. Help support our independent journalism at theguardian.com/sciencepod

‘AI psychosis’: could chatbots fuel delusional thinking?

For more than a decade, scientists have been puzzling over what was causing billions of starfish to dissolve into piles of white goo. Sea star wasting disease has ravaged starfish populations, wiping out 90% of the once common sunflower sea star. Now, researchers have finally identified the culprit. Madeleine Finlay speaks to Dr Melanie Prentice, one of the team to crack the case. She explains the impact the disease has had on the marine environment, how they found the pathogen responsible, and what it means for sea stars’ recovery. Help support our independent journalism at theguardian.com/sciencepod

A decade long mystery - why were billions of starfish turned to goo?

Scientists have found the first robust evidence that people’s genes affect their chances of developing myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), a mysterious and debilitating illness that has been neglected and dismissed for decades by many in the medical community. To find out more, Madeleine Finlay speaks to science editor Ian Sample and to Nicky Proctor, who has ME and took part in the research. She also hears from Beth Pollack, a research scientist at the Massachusetts Institute of Technology who studies ME/CFS and related conditions, about how scientific understanding of the illness has improved and how scientists are transforming this knowledge into ideas about future treatments. Help support our independent journalism at theguardian.com/sciencepod

Is there hope on the horizon for patients with Alzheimer’s?

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