168. Chemistry, Evolved

168. Chemistry, Evolved

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Episode
201 of 202
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59M
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Engelsk
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Frances Arnold pioneered the process of directed evolution — mimicking natural selection to create new enzymes that have changed everything from agriculture to laundry.

SOURCES:Frances Arnold • , professor of chemistry at the California Institute of Technology.

RESOURCES: • " Innovation by Evolution: Bringing New Chemistry to Life • ," by Frances Arnold (Nobel Lecture, 2018). • " Bacteria taught to bond carbon and silicon for the first time • ," by Aviva Rutkin ( New Scientist • , 2016). • " Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life • ," by S. B. Jennifer Kan, Russell D. Lewis, Kai Chen, and Frances H. Arnold ( Science • , 2016). • " The Director of Evolution • ," by Jennifer Ouellette ( Slate • , 2013). • " Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli • ," by Sabine Bastian, Xiang Liu, Joseph T. Meyerowitz, Christopher D. Snow, Mike M. Y. Chen, and Frances H. Arnold ( Metabolic Engineering • , 2011). Gevo • . Provivi • .

EXTRAS: • " How to Help Kids Succeed • ," by People I (Mostly) Admire • (2025). The Levitt Lab • .

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