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Sam Harris

Join neuroscientist, philosopher, and five-time New York Times best-selling author Sam Harris as he explores important and controversial questions about the mind, society, current events, moral philosophy, religion, and rationality—with an overarching focus on how a growing understanding of ourselves and the world is changing our sense of how we should live. 

Sam is also the creator of the Waking Up app. Combining Sam's decades of mindfulness practice, profound wisdom from varied philosophical and contemplative traditions, and a commitment to a secular, scientific worldview, Waking Up is a resource for anyone interested in living a more examined, fulfilling life—and a new operating system for the mind. 

Waking Up offers free subscriptions to anyone who can't afford one, and donates a minimum of 10% of profits to the most effective charities around the world. To learn more, please go to WakingUp.com. 

Sam Harris received a degree in philosophy from Stanford University and a Ph.D. in neuroscience from UCLA.

Making Sense with Sam Harris

Sam Harris speaks with Kathryn Paige Harden about behavioral genetics, moral luck, and the problem of blame. They discuss Harden's book Original Sin, the controversy over Charles Murray and Ezra Klein, why behavioral genetics remains taboo, the meaning of heritability, nature and nurture as feedback loops, why biological explanations can increase blame, psychopathy as a continuum, a hypothetical cure for evil, embryo selection and IVF, and other topics.
 
Related Episode: #212 - A Conversation with Kathryn Paige Harden
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#486 — Luck All the Way Down

Sam Harris speaks with Siddhartha Mukherjee about the science of cancer. They discuss the updated edition of The Emperor of All Maladies, whether cancer is one disease or many, why prevention is so hard, inflammation and air pollution as carcinogens, the myth that cell phones cause cancer, liquid biopsies and Bayesian reasoning, immunotherapy and CAR T cells, drug pricing, the promise of AI in drug discovery, the state of American medical science, and other topics.
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#485 — The New Science of Cancer

Sam Harris speaks with Paul Bloom about our relationships with AI and the future of human connection. They discuss the surprising pace of AI progress, AI companions as a remedy for loneliness, the importance of mattering to other people, digitally resurrecting the dead, whether AI can be conscious, the moral failings of artists, what science actually knows about parenting, the ethics of apology, why late converts from Trump provoke outrage, and other topics.
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#484 — Artificial Intimacy

Sam Harris speaks with Alain de Botton about the psychology of unhappiness, the secular world's discomfort with ecstasy and ritual, psychedelics as a tool for self-discovery, Freud's legacy, AI as the ultimate mirror, the case against meritocracy, the cancel culture purity trap, the psychological meaning of death, and other topics.
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#483 — The Knots We Tie Ourselves Into

In this latest episode of the More From Sam series, Sam and Jaron talk about current events. They discuss topics from Making Sense Community, including one-world government, the value of a degree as AI reshapes careers, and factory farming ethics, along with Mamdani's DSA-aligned candidates, Trump's humiliating capitulation in the Iran deal, the Tulsi Gabbard guru story, and other topics.
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#482 — More From Sam: The Iran Deal, College in the AI Age, Mamdani's DSA, and More

Richard Dawkins presents Sam Harris with the 2026 Richard Dawkins Award at a live Center for Inquiry event. After the tribute, the two friends discuss consciousness and epiphenomenalism, AI and the Turing test, the scientific basis of morality, the failures of democracy and Trump's corruption, the role of philosophy, changing deeply held beliefs, Sam's path to meditation, the legacy of Christopher Hitchens, and other topics.
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#481 — Sam Harris Receives the 2026 Richard Dawkins Award

Sam Harris speaks with economist and Substack writer Noah Smith about the U.S. national debt, wealth inequality, and the economic consequences of AI. They discuss the mechanics of debt and inflation, the case for fiscal austerity, why the U.S. squandered low interest rates, modern monetary theory, how AI may restructure labor and ownership, the anti-billionaire politics of the American left, the degrowth movement and its failures, demographic decline and fertility trends, the role of smartphones in eroding democratic culture, and other topics.
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#480 — The Economics of Everything

Sam Harris speaks with Vinod Khosla about AI, economic disruption, and political risk. They discuss the prospect of mass job displacement, a trillion-dollar policy framework to redistribute AI's gains, the failure of the California wealth tax, the corporate capitulation to Trump, Elon Musk's embrace of white nationalist rhetoric, US-China competition, semiconductor dependence, and other topics.
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#479 — When Robots Take Over

Sam Harris speaks with Robin Carhart-Harris about psychedelic research and its therapeutic potential. They discuss the current state of the field, the FDA denial of MDMA-assisted therapy for PTSD, the critical role of set and setting, risks for vulnerable populations, the REBUS model of how psychedelics work on the brain, the default mode network and ego dissolution, microdosing, the neuroscience of consciousness, DMT entities, and other topics.
 
If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

#478 — The Psychedelic Mind

Warning: This episode contains graphic descriptions of violence against civilians during the October 7 attacks (33:49 - 34:35). Listener discretion is advised.
 
In this latest episode of the More From Sam series, Sam and Jaron talk about current events. They discuss the Trump administration's bungled Iran campaign, the information war surrounding Gaza and October 7, Nicholas Kristof's disputed New York Times report on Israeli prisoner abuse, Sam's controversial take on AI-generated music, OpenAI solving a decades-old math problem, the ethics of concealing GLP-1 use, and other topics.

#486 — Luck All the Way Down

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