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Neuroscientist and author David Eagleman discusses how our brain interprets the world and what that means for us. Through storytelling, research, interviews, and experiments, David Eagleman tackles wild questions that illuminate new facets of our lives and our realities.


Inner Cosmos with David Eagleman

Is AI thinking things it never says aloud? How would we know if a large language model were having a subjective experience? Is there a way to read the 'thoughts' of an LLM? Human brains seem to have a 'global workspace' -- what would it mean if we discovered that AI has something similar? Can you reach inside an LLM to change one of its 'thoughts'? Join Eagleman with Anthropic interpretability researcher Jack Lindsey to talk about what might be going on inside the mind of Claude.

Ep169 "What Is Claude Thinking But Not Saying?" with Jack Lindsey

Could there be a better form of government than the one we have now? As we enter an AI-powered world, when might we choose an AI leader? Will your grandchildren ever vote for a human president, who comes with a political party & the weaknesses of a human, or will they vote for a system that has a jaw-dropping capacity to extract patterns from vast rivers of data, simulate millions of possible futures, & govern with a deeper wisdom than a human could naturally possess? Will we all have personal AI agents that know our strongest political opinions, such that we finally achieve (for the first time at scale) a direct democracy rather than a representative one? Join Eagleman as he explores the future of an AI leader (pros & cons) and where he thinks we’re inevitably heading.

Ep168 "Will it Someday Make Sense to Elect an AI President?"

What happens when old brain circuitry collides with modern tech? Are we heading into an age of abundance, and can abundance create its own psychological problems? Do we need friction in our lives to become better humans? Could curiosity become the most important survival skill of the twenty-first century? What happens to your biological neural networks when artificial neural networks do your thinking for you? Eagleman sits down with author and researcher Steven Kotler to discuss his new book, We Are As Gods.

Ep167 "What Happens With Stone Age Brains + Godlike Tools?" with Steven Kotler

A brain computer interface (BCI) is any technology that allows you to connect your 3 pounds of wetware to a computer. But instead of implanting electrodes via neurosurgery, might the next revolution in BCIs come from something very small, like nanoparticles? Would this allow us to spy on millions (or billions) of neurons talking at once -- and could we do so without opening the skull? Will this allow BCI tech to become as common as smartphones? Join Eagleman as he talks with the company Subsense about why the next brain-computer interface might come from thinking small.

Ep166 "Could the Next Brain Interface Get Sprayed Up Your Nose?" with Tetiana Aleksandrova & Scott Meek

Have you ever spent hours with a thought cycling around in your head? What happens when the brain continuously worries, craves, or replays something without finding the exit? Where does the feeling of being “done” come from? Might depression, addiction, OCD, and PTSD all share the same problem? Is mental freedom just the ability to change states? Join Eagleman with neuroscientist and psychiatrist Jonathan Downar to talk about doom loops and how we might break them.

Ep165 "What's a Doom Loop & How Do You Escape It?" with Jonathan Downar

Does your identity and performance change in different situations? What does this have to do with wondering how you’re being judged? What if polarization grows from uncertainty more than hatred? Might social uncertainty be more common than prejudice? Why do strangers become enemies so easily? Can we engineer more trust into society? Today Eagleman sits down with Stanford social psychologist Claude Steele to explore the hidden psychological forces that shape who we become whenever we wonder how other people see us.

Ep164 "Why Do We Act Differently Around Different People?" With Claude Steele

What is artificial general intelligence (AGI) and how close are we to getting there? What defines the next step, called artificial superintelligence (ASI), and why might the gap between those two be so dangerous? When machines become smarter than us, what roles are left for humanity? Should we think of AI as software, or as something we’re raising like a child? Will tomorrow’s AI destroy us, ignore us, or protect us? This week Eagleman talks with computer scientist & AI researcher Ben Goertzel.

Ep163 "How Quickly Does AI Become Smarter Than Humanity?" with Ben Goertzel

For all of medical history, we’ve tried to persuade sick cells to behave better. What if instead we just swapped them out? Can we insert new brain cells grown from your own skin cells? And what does any of this have to do with sending one’s own cells into space, or rescuing animals on the very brink of extinction? Today we talk with stem cell biologist Jeanne Loring about the exciting next horizons.

Ep162 "What Does Medicine Look Like in Ten Years?" with Jeanne Loring

What do honeybee brains have in common with human brains -- and with the AI that beat the world's best Go player? What simple algorithm has been hiding inside brains for 100s of millions of years? When babies throw food from a high chair again and again, are they being mischievous or are they running physics experiments? And what does any of this have to do with whether dopamine is more than a pleasure molecule, or whether there are laws of physics we have yet to discover, or whether large language models are going to get outdated in favor of a new approach? Join Eagleman with computational neuroscientist Read Montague to explore how very old systems in our brains map onto the future of AI.

Ep161 "What Do Ancient Brains and Future AIs Have in Common?" with Read Montague

re you the author of your thoughts or just their witness? Do we simply watch our thoughts like we watch unfolding dream plots? What if the most familiar thing you experience — yourself — isn’t really there? If that’s the case, why does the experience of the self feel so solid that it often takes a lifetime to notice something strange? Why would evolution invent the feeling of a self at all? Join Eagleman with philosopher & neuroscientist Sam Harris as they explore the self, meditation, dreams, movies, and much more.

Ep166 "Could the Next Brain Interface Get Sprayed Up Your Nose?" with Tetiana Aleksandrova & Scott Meek

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