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iHeartPodcasts


Neuroscientist and author David Eagleman discusses how our brain interprets the world and what that means for us. Through storytelling, research, interviews, and experiments, David Eagleman tackles wild questions that illuminate new facets of our lives and our realities.


Inner Cosmos with David Eagleman

For all of medical history, we’ve tried to persuade sick cells to behave better. What if instead we just swapped them out? Can we insert new brain cells grown from your own skin cells? And what does any of this have to do with sending one’s own cells into space, or rescuing animals on the very brink of extinction? Today we talk with stem cell biologist Jeanne Loring about the exciting next horizons.

Ep162 "What Does Medicine Look Like in Ten Years?" with Jeanne Loring

What do honeybee brains have in common with human brains -- and with the AI that beat the world's best Go player? What simple algorithm has been hiding inside brains for 100s of millions of years? When babies throw food from a high chair again and again, are they being mischievous or are they running physics experiments? And what does any of this have to do with whether dopamine is more than a pleasure molecule, or whether there are laws of physics we have yet to discover, or whether large language models are going to get outdated in favor of a new approach? Join Eagleman with computational neuroscientist Read Montague to explore how very old systems in our brains map onto the future of AI.

Ep161 "What Do Ancient Brains and Future AIs Have in Common?" with Read Montague

re you the author of your thoughts or just their witness? Do we simply watch our thoughts like we watch unfolding dream plots? What if the most familiar thing you experience — yourself — isn’t really there? If that’s the case, why does the experience of the self feel so solid that it often takes a lifetime to notice something strange? Why would evolution invent the feeling of a self at all? Join Eagleman with philosopher & neuroscientist Sam Harris as they explore the self, meditation, dreams, movies, and much more.

Ep160 "Do You Really Have a Self?" with Sam Harris

Could a tiny injury to your brain change your personality? If your friends didn’t know something had happened in your brain, would they just think you're choosing to act strangely? What if the self is nothing but a fragile coalition of neural processes? Join Eagleman today with Masud Husain, a neurologist and neuroscientist at Oxford, to explore fascinating case studies about how changes in the brain lead to changes in the self.

Ep159 "If Your Brain Changed Slightly, Would You Still Be You?" with Masud Husain

When AI gets the right answer, how do we know it got there the right way? Why do we assume that fluent language means intelligence? What do infants and chatbots have in common? What do AI’s mistakes teach us about our own minds? And what does any of this have to do with Frankenstein’s creature, why some people wear a stop sign on their T-shirt, or smiling monkeys? Join Eagleman today with computer scientist Melanie Mitchell, a professor at the Santa Fe Institute who’s working to bridge AI and cognitive science.

Ep158 "What do babies, animals, and AI have in common?" with Melanie Mitchell

How can we use 26 symbols to capture everything in the cosmos of human experience? Where do our written symbols in English come from? What ancient ghosts are still hiding inside the letters you read every day? Does learning to read reconfigure the circuitry of your brain? Does dyslexia reveal how unnatural reading really is? And could AI freeze the evolution of language for the first time in history? Today we dive into the alphabet with linguist Danny Bate, who’s just written a book on the surprising history of every letter.

Ep157 "Where Did the Letter "A" Come From?" with Danny Bate

Why do we read so much into how a robot moves, and what does that tell us about human brains? Why did our history make us so sensitive to movement? Why do we trust graceful motion? Should we make a robot 'look' at an object it’s about to pick up, even if it doesn’t need to? Is movement the original form of animal intelligence? Join Eagleman with guest Catie Cuan, a roboticist, dancer, and choreographer. Catie’s an expert on the strange social interface between humans and machines, and she’s gotten there by dancing with robots.

Ep156 What Do We Learn About AI by Dancing with Robots? with Catie Cuan

Why do brains generate strange thoughts sometimes? And why do some brains refuse to let go of those thoughts? Today we'll talk about Obsessive Compulsive Disorder (OCD) with expert Jon Hershfield, getting a view from the inside and the outside. Why do some people lock the door but go back repeatedly to check it, and still have a feeling of uncertainty that it’s locked? Why do some people wash their hands over and over and never feel that they reach a point when it’s “done”. How, for some people, are intrusive thoughts like junkmail that the brain just cant help opening? We’ll see how obsessive thoughts can get caught in loops, and how those loops might therapeutically be broken.

Ep155 "Why Can’t Some People Stop Thinking Certain Thoughts?" with Jon Hershfield

What if your brain got stuck in sadness and never reset? What does it feel like when joy disappears completely? Can a person love their family deeply and still want to die? What do you do when treatment after treatment fails? What if the difference between despair and recovery is electrical? How can we better recognize invisible struggles in those around us? Join Eagleman with guest Jon Nelson, a man who suffered for years under the grip of depression, and finally found a science-fiction like treatment which gave him relief.

Ep154 "Can a Depressed Brain Find Its Way Out?" with Jon Nelson

Week 2 of Mental Health Awareness month: Anxiety is close to everyone’s experience, either because you've had it or someone close to you has. Does your brain accidentally teach itself to stay anxious by looping on the same fears? Is anxiety helping you perform better, or does it make everything harder? Is it possible to unlearn worry the same way you learned it? Join Eagleman with Dr. Jud Brewer, who suffered with anxiety as a young man... and then became a psychiatrist and neuroscientist who studies anxiety and developed a very different approach to its treatment.

Ep162 "What Does Medicine Look Like in Ten Years?" with Jeanne Loring

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