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Ask Iliza Anything

Everyone deserves that best friend who delivers blunt advice with impunity. Comedian, writer, and actor Iliza Shlesinger is that friend. She has built a cult-like following of listeners seeking her hilarious take on their problems. Every week, people submit their burning questions to the show, with topics ranging from bad coworkers, psychotic bridesmaids, and a mother-in-law who won't move out to faking an accent and diarrhea etiquette. Iliza's answers range from wise and heart-felt to rage-fueled and off-the-wall. She enjoys nothing more than giving incisive life advice to total strangers, sometimes with a celebrity guest in tow. It's always entertaining, so go ahead: Ask Iliza Anything.

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A straight man wrote in AND an inheritance is being held hostage. 
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We Are Not The Brother

An unsupportive man is keeping a woman from owning land and Iliza continues to think everyone is lying. 
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Ask Andy Gump

Iliza digs into the problems of gaining your sister's approval and dealing with a friend's boyfriend who SPLITS ICE CREAM BARS. 
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You Have A Life To Plan

Iliza helps a mom worried about her kid's college plans and does some tough math to figure out another mother's ideal nanny situation. 

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Office Hours

One listener finds a naked photo of their MIL while another (Sasha!) joins Iliza on the show for the new Be Our Guest segment!
 Get a copy of Ronnie Antik's new book: Heartbeats: Love, Secrets and the Unraveling of Destiny 
 The Rebecca Serle episode mentioned is She Said, She Said from March 20, 2024. 
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Take Back Your Bear

A bevy of brand-new questions involve befriending a therapist and how to raise twins. 
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We Both Love The Name Hannibal

Iliza tackles in-depth questions about deserving better from your partner and how to handle an injury caused by a friend. 
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Reread Your Email

Iliza advises listeners on taking curling too seriously and appropriate mother-of-the-bride attire.
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It's Got The Word Pickle In It

We get into some good old-fashioned drama with questions about dating a friend's crush and working for someone you hooked up with. 
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Graphic Communication

A FULL FOLLOW-UP episode! We check in on question askers past and see where Iliza's advice has left them, and where they might have buried the lead. 
 Episodes where the questions originally aired:
 Fred is cheating on Wilma: Don't Google BTK (2/18/2026)
 Skiing with a Tinder match: Fruit Flowers Look Dorky (2/4/2026)
 Telling on a cheating woman: Fruit Flowers Look Dorky (2/4/2026)
 Catholic sister wedding skipper: Full Baby Butthole (1/28/2026)
 Employee given an unfair review: We've Got A Dalmatian Mix In The Back (4/10/2024)
 Healthcare sister doing drugs: Patrapple (6/11/2025)
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Ugly Wilma Needs To Know

Iliza is mildly impressed by a 90-year-old f-boy and shares the one pose she will NOT do in a photo. 
 
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Hitting A Fly With A Hammer

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