What really works when it comes to preventing and dealing with mental health difficulties? Can a world exist in which no one is held back by mental health problems.? That’s the vision of Professor Miranda Wolpert Head of the Mental Health Priority Area at the Wellcome Trust. With £200million to spend over five years, Miranda Wolpert and her team are taking a radical new approach to addressing anxiety and depression in 14- to 24-year-olds. Claudia hears about her new vision in addressing mental health problems in young people

Sleep problems are common in adolescence, and often related to anxiety and depression. But one factor which might be affecting mental health in people in their twenties is how they slept as teenagers, according to new research from Faith Orchard - lecturer at the University of Sussex. She disentangles exactly what is going on and teases apart the specific sleeping difficulties involved in the complex relationship between sleep, anxiety and depression.

We use various mental shortcuts to save our brains effort. One of those is that when we’ve made a choice in the past and rejected one option, we carry on rejecting that option and downgrade the thing we didn’t choose and actively avoid it if we are offered it again. And until now what wasn’t realised was that infants who of course have far less sophisticated thinking processes, do it too. Does this mean it’s intuitive, rather than something we learn to do? Alex Silver from the University of Pittsburgh dissects the evidence

Producer Adrian Washbourne