Lanie was a Lost Kid, a toddler found by the side of the road, with no one to claim her. She ended up in the Neighborlee Children's Home, where her long journey to become a semi-pseudo-superhero began. She and her friend Kurt, and later Felicity, made up the "rules" for what they were and what they could do as they went along. Most of the time, they borrowed them from comic books.

Lanie could kinda-sorta fly and move things with telekinesis. Kurt could invent and make broken machines work when all mechanical laws said they shouldn't. Felicity gave off uncontrollable EM bursts and controlled dogs. Where the trio came from and how they got to Neighborlee faded into the background when faced with the really big questions: Why were they the way they were and how could they do the things they did? Were they aliens? Genetic experiments? Mutations? Should they look for a spaceship? Should they fear the Men in Black or the CIA?

Adventures and misadventures tested their imagination, their loyalty, and their courage as they explored their abilities and their world. And one thing became perfectly clear: the Lost Kids were as necessary to guard Neighborlee from the rest of the world, as they were vital to protect the rest of the world from the everyday weirdness and magic of Neighborlee.