The Role of Chromenes in Drug Discovery and Development

Chromene is a naturally abundant heterocyclic compound found in alkaloids, tocopherols, terpenes and other compounds. Its derivatives can be used as a scaffold that exhibits pharmacological activity in the human body.

Chromene drugs and related bioactive molecules are the prime focus of this reference. It presents 13 thoroughly researched chapters that comprehensively cover all aspects about the molecule. Starting with a detailed introduction to its role and importance in drug discovery, the book goes into the details of chromene structure, synthesis and pharmacology. Readers can gain knowledge of different commercial medicines based on chromene and its pharmacological activity against different diseases. The elaborate topics in the book will help researchers working on chromene based drugs.

Key highlights of the book include:

- Complete coverage of chromene’s role in nature and drug development with references to historical background and current developments

- References to commercial and preclinical drugs and patents of interest

- Explanation of chromene bioacivity in different diseases (antioxidant, antidiabetic, antinflammatory, antibacterial and antifungal activities, antitumour, immunomodulatory activity)

- Explanation of chromene activity against SARS-Cov2

© 2000 Bentham Science Publishers (E-bog): 9789815124330

Udgivelsesdato

E-bog: 24. januar 2000